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An artificial intelligence platform for predicting the
composition of extraordinary lipid nanoparticles

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Publications

Active pharmaceutical ingredient (API)

miRNA is a therapeutic active pharmaceutical ingredient designed to modulate disease-specific
gene expression by being encapsulated in artificial exosomes.
  • Sunyoung Park†, Yeo-Jun Yoon†, Yongpyo Hong, Jianning Yu, Jae-Min Cho, Ye Jin Jeong, Haeun Yu,
    Hyorim Jeong, Hyunjin Lee, Seungyeon Hwang, Won-Gun Koh, Ji Yeong Yang, Kyung-A Hyun, Hyo-Il Jung*,
    Jae-Yol Lim*, Bioactive Materials (2025), 44, 229-247 (IF:18.0, JCR:0.9%)     Link : https://www.sciencedirect.com/science/article/pii/S2452199X25000192

Microfluidic chip

A microfluidic chip is a miniature lab-on-a-chip platform with fine channel structures that control
the flow of fluids with great precision, enabling the generation and encapsulation of artificial exosomes.
  • JaejeungKim† , Do Hyun Lee† , HyunjoSeo† , Hyun-JinLee, GeonhaKim, Cheng Nie, YongpyoHong, Yeo-Jun
    Yoon, Jae-YolLim, SeongJun Park, Ji YeongYang, SeoyeonChoi, SunyoungPark*, and Hyo-Il Jung*, Small (2025),
    21, e06162. (IF:12.1, JCR:7.2%)     Link : https://onlinelibrary.wiley.com/doi/10.1002/smll.202506162

Artificial intelligence

Artificial intelligence is a computational system that learns from data, and in this platform it
predicts and recommends the optimal composition of artificial exosomes.
  • Seongmin Ha †, Do Hyun Lee †, Taehoon Lee †, Hairi Jiang †, Hyun-jin Lee, Seungbum Seo, Ji Yeong Yang,
    Sunyoung Park, Sung-Gyu Park, Joonchul Shin*, and Hyo-Il Jung*, Nano Convergence (2026), 13, 2. (IF:11.0, JCR:14.1%)     Link : https://doi.org/10.1186/s40580-026-00531-7